About GMA and MOVIVA®
Introduction For many people living with obesity, persistent hunger signals and cravings make long-term weight management difficult. GMA is an incisionless, minimally invasive endoscopic procedure, that targets the gastric fundus, the main site of ghrelin production – the so-called hunger hormone. By reducing ghrelin levels, patients experience less hunger. At the same time, the ablated tissue shrinks the fundus. Together, these effects can support controlled weight reduction.
GMA with MOVIVA®: Targeting hunger at its source MOVIVA® is an advanced hybrid instrument designed for GMA. It combines two key functions in one product. Injection of a protective submucosal fluid cushion that protects deeper tissue layers from thermal injury and superficial thermal ablation of the mucosa using argon plasma coagulation (APC). MOVIVA®’s dedicated moveAPD mode ensures broad and consistent argon plasma coagulation. Another strength of MOVIVA® lies in its enhanced injection capabilities, particularly in tangential positions, which are often challenging in endoscopic settings.
Early clinical experience with GMA
Clinical evidence indicates that fundal GMA using MOVIVA induces weight loss. GMA alone achieves 7.7% total body weight loss (TBWL) after 6 months in early studies.1
GMA may be used either on its own or in combination with endoscopic sleeve gastroplasty (ESG). When combined, early data indicate further improvements, with up to 24% TBWL. reported after 12 months – approaching outcomes seen with surgical sleeve gastrectomy, while remaining far less invasive.2,3
Visit the website for more information on MOVIVA® [MOVIVA® Turn down the food noise]. MOVIVA® is currently available in CE and CE-related markets.
Sources:
1Maselli, Daniel B et al. “Endoscopic Gastric Fundal Mucosal Ablation Induces Weight Loss in Adults With Obesity.” Gastroenterology vol. 167,7 (2024): 1457-1459.e3. doi:10.1053/j.gastro.2024.08.008
2McGowan, C. E., et al. (2025). “Combination gastric fundus mucosal ablation and endoscopic sleeve gastroplasty: Results from two first-in-human studies.” Gastrointestinal Endoscopy, Volume 101, Issue 5, S58.
3Gadi SR, et al. (2026) “Gastric fundal mucosal ablation followed by endoscopic sleeve gastroplasty in adults with obesity: a first-in-human two-phase pilot clinical trial.” Endoscopy, 2026. DOI: 10.1055/a-2823-8603
About Erbe Elektromedizin
In 2026 the Erbe Elektromedizin GmbH celebrates its 175th anniversary under the motto “Progress with Purpose.” Since 1851 Erbe Elektromedizin GmbH develops, manufactures, and distributes surgical instruments and devices worldwide, while providing services for professional use of these products in a diverse range of medical disciplines. Physicians, clinical teams and patients around the world rely on medical technology from Erbe. The instruments and devices find use in almost all specialist areas. They are based on electrosurgery combined with other Erbe technologies. Hybrid solutions enable new, innovative applications in medicine.
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